GTX48698
ABCB6 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX48698
- Zusätzliche Namen:
- ATP binding cassette subfamily B member 6 (Langereis blood group) , ABC , LAN , MTABC3 , PRP , umat
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Canine, Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to an internal region near amino acids 430-465 of human ABCB6 protein.
- Uniprot:
- Q9NP58
- Synonyme:
- ABC;ABC-type heme transporter ABCB6;ATP-binding cassette half-transporter;ATP-binding cassette sub-family B member 6;ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group);LAN;mitochondrial ABC transporter 3;mt-ABC transporter 3;MTABC3;P-glycoprotein-related protein;PRP;truncated ATP binding cassette subfamily b member 6;ubiquitously-expressed mammalian ABC half transporter;umat
- Weitere Details:
- ABCB6 (ATP-binding cassette sub-family B member 6, also known as mitochondrial precursor ABC transporter 3, Mt-ABC transporter 3, and ABC transporter umat) is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABCB6 is a membrane-associated protein that transports various molecules across the extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, DR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily confer multi-drug resistance (MDR) to cancer cells and are also involved in antigen presentation. ABCB6 also likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
- Versandbedingungen:
- Blue Ice