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  1. Alles ansehen
  2. Polyclonal

GTX48690

MIP3 alpha antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX48690
Zusätzliche Namen:
chemokine (C-C motif) ligand 20 , CKb4 , LARC , MIP-3A , MIP-3[a] , MIP3A , ST38 , Scya20 , exodus-1
Anwendung:
ELISA, WB
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Mouse
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Mouse, Rat
Buffer:
20mM Potassium Phosphate, 150mM NaCl, no preservatives.
Immunogen:
Full length recombinant mouse MIP-3 alpha protein.
Uniprot:
O89093
Synonyme:
beta-chemokine exodus-1;C-C motif chemokine 20;CC chemokine LARC;CC chemokine ST38;CKb4;exodus;exodus-1;LARC;liver and activation-regulated chemokine;macrophage inflammatory protein 3 alpha;MI;MIP;MIP-3;MIP-3-alpha;MIP-3[a];MIP-3A;MIP3A;Scya;Scya20;small inducible cytokine subfamily A20;small-inducible cytokine A20;ST3;ST38
Weitere Details:
MIP-3a (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3a inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3a also possesses antibacterial activity against E.coli and S.aureus. MIP-3a is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Versandbedingungen:
Blue Ice