STAT5A (phospho Tyr694) antibody [5F6.F1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX48647
Zusätzliche Namen:: signal transducer and activator of transcription 5A , AA959963 , STAT5
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human, Mouse
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
Immunogen:: Synthetic peptide corresponding to residues surrounding Y694 of mouse STAT5a protein.
Klon:: 5F6.F1
Uniprot:: P42230
Synonyme:: AA959963;Mammary gland factor;mammary gland factor STAT5A;signal transducer and activator of transcription 5A;STA;STAT5
Weitere Details:: Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5and Stat5. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus.