GTX48519
PSMD10 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX48519
- Zusätzliche Namen:
- proteasome 26S subunit, non-ATPase 10 , dJ889N15.2 , p28 , p28(GANK)
- Anwendung:
- Flow Cytometry, WB, IF, ICC
- Konzentration:
- 0.97 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Bovine, Fish, Human, Mouse, Porcine, Rat
- Buffer:
- Tris-Glycine, 150mM NaCl, 0.05% Sodium azide.
- Immunogen:
- A synthetic peptide made to an internal portion of the human Gankyrin protein sequence (between residues 100-200). [UniProt# O75832]
- Uniprot:
- O75832
- Synonyme:
- 26S proteasome non-ATPase regulatory subunit 10;26S proteasome regulatory subunit p28;ankyrin repeat protein;dJ889N15.2;gankyrin;hepatocellular carcinoma-associated protein p28-II;p28;p28(GANK);proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
- Weitere Details:
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice