GTX47608
DUSP1 antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX47608
- Zusätzliche Namen:
- dual specificity phosphatase 1 , CL100 , HVH1 , MKP-1 , MKP1 , PTPN10
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human, Mouse
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence SYLQSPITTSPSC, from the C Terminus of the protein sequence according to NP_004408.1.
- Uniprot:
- P28562
- Synonyme:
- CL 100;CL100;dual specificity protein phosphatase 1;dual specificity protein phosphatase hVH1;HVH1;MAP kinase phosphatase 1;mitogen-activated protein kinase phosphatase 1;MKP-1;MKP1;protein-tyrosine phosphatase CL100;PTPN10;serine/threonine specific protein phosphatase
- Weitere Details:
- The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017]
- Versandbedingungen:
- Blue Ice