GTX47433
PRMT6 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX47433
- Zusätzliche Namen:
- protein arginine methyltransferase 6 , HRMT1L6
- Anwendung:
- ChIP, WB
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to an Internal region of Human PRMT6
- Uniprot:
- Q96LA8
- Synonyme:
- heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6;histone-arginine N-methyltransferase PRMT6;HMT1 hnRNP methyltransferase-like 6;HRMT1L6;protein arginine N-methyltransferase 6
- Weitere Details:
- The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
- Versandbedingungen:
- Blue Ice