GTX47135
PRODH2 antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX47135
- Zusätzliche Namen:
- proline dehydrogenase 2 , HSPOX1 , HYPDH
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a C-terminal region of Human PRODH2
- Uniprot:
- Q9UF12
- Synonyme:
- HSPOX1;hydroxyproline dehydrogenase;HYPDH;kidney and liver proline oxidase 1;probable proline dehydrogenase 2;probable proline oxidase 2;proline dehydrogenase (oxidase) 2
- Weitere Details:
- The protein encoded by this gene catalyzes the first step in the catabolism of trans-4-hydroxy-L-proline, an amino acid derivative obtained through food intake and collagen turnover. One of the downstream products of this catabolism is glyoxylate, which in people with disorders of glyoxalate metabolism can lead to an increase in oxalate levels and the formation of calcium-oxalate kidney stones. Therefore, this gene may serve as a therapeutic target against primary hyperoxalurias (PH). This gene is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme that catalyzes the first step in proline catabolism. [provided by RefSeq, Jan 2017]
- Versandbedingungen:
- Blue Ice