GTX46906
RNF128 antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX46906
- Zusätzliche Namen:
- ring finger protein 128 , GRAIL
- Anwendung:
- WB
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a C-terminal region of Human RNF128
- Uniprot:
- Q8TEB7
- Synonyme:
- E3 ubiquitin-protein ligase RNF128;gene related to anergy in lymphocytes protein;GRAIL;RING finger protein 128;ring finger protein 128, E3 ubiquitin protein ligase;RING-type E3 ubiquitin transferase RNF128
- Weitere Details:
- The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice