GTX46887
IBRDC1 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX46887
- Zusätzliche Namen:
- ring finger protein 217 , C6orf172 , IBRDC1 , OSTL , dJ84N20.1
- Anwendung:
- WB
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to an Internal region of Human IBRDC1.
- Uniprot:
- Q8TC41
- Synonyme:
- C6orf172;dJ84N20.1;IBR domain containing 1;IBR domain-containing protein 1;IBRDC1;opposite STL;OSTL;probable E3 ubiquitin-protein ligase RNF217;RING finger protein 217
- Weitere Details:
- This protein encoded by this gene is a member of the RING1-IBR-RING24 (RBR) ubiquitin protein ligase family, and it belongs to a subfamily of these proteins that contain a transmembrane domain. This protein can interact with the HAX1 anti-apoptotic protein via its C-terminal RING finger motif, which suggests a role in apoptosis signaling. It is thought that deregulation of this gene can be a mechanism in leukemogenesis. Mutations in the region encoding the protein GXXXG motif, which appears to be necessary for protein self-association, have been found in human cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
- Versandbedingungen:
- Blue Ice