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  2. Polyclonal

GTX46448

CDH12 antibody, Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX46448
Zusätzliche Namen:
cadherin 12 , CDHB
Anwendung:
WB
Konzentration:
0.5-1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
PBS, 2% Sucrose, 0.09% Sodium azide.
Immunogen:
A synthetic peptide corresponding to an Internal region of Human CDH12
Uniprot:
P55289
Synonyme:
Br-cadherin;Brain cadherin;brain-cadherin;cadherin-12;cadherin, neural type, 2;CDHB;N-cadherin 2;neural type cadherin 2;neuronal cadherin 2
Weitere Details:
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Nov 2015]
Versandbedingungen:
Blue Ice