GTX45916
NFAT2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX45916
- Zusätzliche Namen:
- nuclear factor of activated T cells 1 , NF-ATC , NF-ATc1.2 , NFAT2 , NFATc
- Anwendung:
- WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.05% Sodium azide.
- Immunogen:
- Amino acids 264-282 (NKRKYSLNGRQPPYSPHHS) of human NFATc1 were used as immunogen for this antibody.
- Uniprot:
- O95644
- Synonyme:
- NF-ATC;NF-ATc1.2;NFAT transcription complex cytosolic component;NFAT2;NFATc;nuclear factor of activated T-cells 'c';nuclear factor of activated T-cells, cytoplasmic 1;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- Weitere Details:
- The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice