HLA-DPA1 antibody, Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX45903
Zusätzliche Namen:: major histocompatibility complex, class II, DP alpha 1 , DP(W3) , DP(W4) , DPA1 , HLA-DP1A , HLADP , HLASB , PLT1
Anwendung:: WB
Konzentration:: 0.5-1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 2% Sucrose, 0.09% Sodium azide.
Immunogen:: A synthetic peptide corresponding to an Internal region of Human HLA-DPA1
Uniprot:: P20036
Synonyme:: DP(W3);DP(W4);DPA1;HLA class II histocompatibility antigen, DP alpha 1 chain;HLA DPA1;HLA-DP1A;HLA-DPA;HLA-DPA1*01:03:01:New;HLA-DPA1*02:01:01:NEW;HLA-DPB1;HLA-SB alpha chain;HLADP;HLASB;MHC class II antigen DP alpha chain;MHC class II DP alpha chain;MHC class II DP3-alpha;MHC class II DPA1;MHC class II HLA-DPA1 antigen;MHC class II protein;PLT1
Weitere Details:: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice