GTX45892
Porimin antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX45892
- Zusätzliche Namen:
- transmembrane protein 123 , KCT3 , PORIMIN , PORMIN
- Anwendung:
- WB
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a C-terminal region of Human Porimin.
- Uniprot:
- Q8N131
- Synonyme:
- KCT-3;KCT3;keratinocytes associated transmembrane protein 3;Keratinocytes-associated transmembrane protein 3;porimin;PORMIN;pro-oncosis receptor inducing membrane injury;serine/threonine-rich receptor;Transmembrane protein 123
- Weitere Details:
- This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice