GTX45122
KSHV GPCR antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX45122
- Zusätzliche Namen:
- Kaposi's sarcoma-associated herpesvirus GPCR , HHV-8 GPCR , Human herpesvirus 8 GPCR
- Anwendung:
- Flow Cytometry
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Virus
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Buffer:
- PBS, 0.1% Sodium azide.
- Immunogen:
- Recombinant fragment - amino acids 1-41 of HHV8 GPCR (N-terminal)
- Weitere Details:
- Kaposi's sarcoma-associated herpesvirus (KSHV, or human herpesvirus 8, HHV8), is a gamma herpesvirus that contain an open reading frame encoding a G protein-coupled receptor (GPCR) with putative 7 transmembrane domains. This GPCR has been shown to bind a number of chemokines including IL8, NAP2, PF4, MGSA/Gro alpha, I309, RANTES, MCP1, and MIP1 beta. The receptor is constitutively activated without chemokine binding, and it stimulates cell proliferation. KSHV GPCR is also a viral oncogene that stimulates angio-genesis through induction of VEGF expression. IP10, a chemokine, can inhibit constitutively activated KSHV GPCR.
- Versandbedingungen:
- Blue Ice