GTX44869
A2BP1 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX44869
- Zusätzliche Namen:
- RNA binding fox-1 homolog 1 , 2BP1 , A2BP1 , FOX-1 , FOX1 , HRNBP1
- Anwendung:
- WB
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to an Internal region of Human A2BP1
- Uniprot:
- Q9NWB1
- Synonyme:
- 2BP1;A2BP1;ataxin 2-binding protein 1;Ataxin-2-binding protein 1;FOX-1;fox-1 homolog A;fox-1-like RNA-binding protein 1;FOX1;hexaribonucleotide-binding protein 1;HRNBP1;RNA binding protein fox-1 homolog 1;RNA binding protein, fox-1 homolog 1
- Weitere Details:
- The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
- Versandbedingungen:
- Blue Ice