GTX44679
MRP2 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX44679
- Zusätzliche Namen:
- ATP-binding cassette, sub-family C (CFTR/MRP), member 2 , AI173996 , Abc30 , Cmoat , Mrp2 , cMRP
- Anwendung:
- WB
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to an Internal region of Mouse MRP2
- Uniprot:
- Q8VI47
- Synonyme:
- Abc30;AI173996;ATP-binding cassette sub-family C member 2;canalicular multispecific organic anion transporter 1;Cmo;Cmoat;cMRP;Mr;Mrp2;multidrug resistance protein 2;multidrug resistance-associated protein 2
- Weitere Details:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the canalicular surface of the hepatocyte and in biliary transport, and appears to contribute to drug resistance in mammalian cells. Several different mutations in the human gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. Alternative splice variants have been observed for this gene; however, they have not been fully described. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice