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GTX43752

Coagulation factor III/Tissue Factor antibody [CLB/TF-5] (FITC)

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX43752
Zusätzliche Namen:
coagulation factor III, tissue factor , CD142 , TF , TFA
Anwendung:
Flow Cytometry
Konzentration:
0.1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein A Purified
Lagerbedingungen:
2-8[o]C Aliquot. Avoid freeze/thaw cycles. Protect from light., -20[o]C Aliquot. Avoid freeze/thaw cycles. Protect from light.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
TBS, 1% BSA, 0.09% Sodium azide.
Immunogen:
coagulation factor III, tissue factor
Klon:
CLB/TF-5
Uniprot:
P13726
Synonyme:
CD142;Coagulation factor III;coagulation factor III (thromboplastin, tissue factor);TF;TFA;Thromboplastin;tissue factor
Weitere Details:
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Versandbedingungen:
Blue Ice