GTX42600
C4c antibody [10-12]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX42600
- Zusätzliche Namen:
- C4B1 Antibody , CO4 Antibody , C4B2 Antibody , C4BD Antibody , C4B3 Antibody , C4B Antibody , complement component 4B (Chido blood group) Antibody , CPAMD3 Antibody , CH Antibody , C4B5 Antibody , C4F Antibody , C4B12 Antibody
- Anwendung:
- ELISA, Flow Cytometry, WB, IHC-Fr
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Borate buffered saline, 0.09% Sodium azide.
- Immunogen:
- Purified human C4c.
- Klon:
- 10-12
- Synonyme:
- basic complement C4;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3;C4B_2;C4B1;C4B12;C4B2;C4B3;C4B5;C4BD;C4F;CH;Chido form of C4;CO4;complement C4-B;complement C4B1a;complement component 4B (Chido blood group);CPAMD3
- Weitere Details:
- This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice