KCNQ4 antibody [S43-6]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX41990
Zusätzliche Namen:: potassium voltage-gated channel subfamily Q member 4 , DFNA2 , DFNA2A , KV7.4
Anwendung:: WB, IHC-P, IHC-Fr, IF, ICC, IP
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 50% Glycerol, no preservatives.
Immunogen:: Fusion protein amino acids 2-77 of human KCNQ4, accession number P56696
Klon:: S43-6
Uniprot:: P56696
Synonyme:: DFNA2;DFNA2A;KQT-like 4;KV7.4;potassium channel KQT-like 4;potassium channel subunit alpha KvLQT4;potassium channel, voltage gated KQT-like subfamily Q, member 4;potassium voltage-gated channel subfamily KQT member 4;potassium voltage-gated channel, KQT-like subfamily, member 4;Voltage-gated potassium channel subunit Kv7.4
Weitere Details:: The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice