GTX41386
CDC27 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX41386
- Zusätzliche Namen:
- cell division cycle 27 , ANAPC3 , APC3 , CDC27Hs , D0S1430E , D17S978E , H-NUC , HNUC , NUC2
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding amino acids 415-445 of Human cdc27.
- Uniprot:
- P30260
- Synonyme:
- ANAPC3;anaphase promoting complex subunit 3;Anaphase-promoting complex subunit 3;anaphase-promoting complex, protein 3;APC3;CDC27 homolog;CDC27Hs;cell division cycle 27 homolog;cell division cycle protein 27 homolog;D0S1430E;D0S1430E, D17S978E;D17S978E;H-NUC;HNUC;NUC2;nuc2 homolog
- Weitere Details:
- Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.
- Versandbedingungen:
- Blue Ice