GTX41272
TL1A antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX41272
- Zusätzliche Namen:
- TNF superfamily member 15 , TL1 , TL1A , TNLG1B , VEGI , VEGI192A
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ion Exchange
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- TL1A antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TL1A.The immunogen is located within amino acids 60 - 110 of TL1A.
- Uniprot:
- O95150
- Synonyme:
- TL1;TL1A;TNF ligand-related molecule 1;TNF superfamily ligand TL1A;TNLG1B;tumor necrosis factor (ligand) superfamily, member 15;tumor necrosis factor ligand 1B;tumor necrosis factor ligand superfamily member 15;tumor necrosis factor superfamily member 15;vascular endothelial cell growth inhibitor;vascular endothelial growth inhibitor-192A;VEGI;VEGI192A
- Weitere Details:
- Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl1, Apo3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NFK KappaB activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL1.
- Versandbedingungen:
- Blue Ice