GTX38554
API5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX38554
- Zusätzliche Namen:
- apoptosis inhibitor 5 , AAC-11 , AAC11
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- 0.001% Na₂HPO₄, 0.0045% NaCl, 0.025% BSA, 0.00025% Thimerosal, 0.00025% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminus of human API5 (487-504aa KYSSNLGNFNYERSLQGK)(b), different from the related mouse sequence by one amino acid.
- Uniprot:
- Q9BZZ5
- Synonyme:
- AAC-11;AAC11;antiapoptosis clone 11 protein;apoptosis inhibitor 5;cell migration-inducing gene 8 protein;Fibroblast growth factor 2-interacting factor;fibroblast growth factor 2-interacting factor 2;FIF;migration-inducing protein MIG8;Protein XAGL
- Weitere Details:
- This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- Versandbedingungen:
- Blue Ice