GTX37416
mGluR1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX37416
- Zusätzliche Namen:
- glutamate metabotropic receptor 1 , GPRC1A , MGLU1 , MGLUR1 , PPP1R85 , SCA44 , SCAR13
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 10mM TBS, 0.5% BSA, 25% Glycerol, 0.015% ProClin 300.
- Immunogen:
- KLH conjugated synthetic peptide derived between 661-740 amino acids of human GRM1
- Uniprot:
- Q13255
- Synonyme:
- glutamate receptor, metabotropic 1;GPRC1A;metabotropic glutamate receptor 1;MGLU1;MGLUR1;PPP1R85;protein phosphatase 1, regulatory subunit 85;SCA44;SCAR13
- Weitere Details:
- This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Versandbedingungen:
- Blue Ice