GTX37395
KIF14 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX37395
- Zusätzliche Namen:
- kinesin family member 14 , MCPH20 , MKS12
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Bovine, Canine, Human, Mouse, Rat, Equine
- Buffer:
- 10mM TBS, 0.5% BSA, 25% Glycerol, 0.015% ProClin 300.
- Immunogen:
- KLH conjugated synthetic peptide derived between 465-540 amino acids of human KIF14
- Uniprot:
- Q15058
- Synonyme:
- epididymis secretory sperm binding protein;kinesin-like protein KIF14;MCPH20;MKS12
- Weitere Details:
- This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
- Versandbedingungen:
- Blue Ice