GTX37363
REST antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX37363
- Zusätzliche Namen:
- RE1 silencing transcription factor , DFNA27 , GINGF5 , HGF5 , NRSF , WT6 , XBR
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Fish, Human, Mouse, Rat
- Buffer:
- 10mM TBS, 0.5% BSA, 25% Glycerol, 0.015% ProClin 300.
- Immunogen:
- KLH conjugated synthetic peptide derived between 541-440 amino acids of human NRSF/REST
- Uniprot:
- Q13127
- Synonyme:
- DFNA27;GINGF5;HGF5;neural-restrictive silencer factor;neuron restrictive silencer factor;NRSF;RE1-silencing transcription factor;repressor binding to the X2 box;WT6;X2 box repressor;XBR
- Weitere Details:
- This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
- Versandbedingungen:
- Blue Ice