GTX35206
NCOA2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX35206
- Zusätzliche Namen:
- nuclear receptor coactivator 2 , GRIP1 , KAT13C , NCoA-2 , SRC2 , TIF2 , bHLHe75
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 550-820 of human NCOA2 (NP_006531.1).
- Uniprot:
- Q15596
- Synonyme:
- bHLHe75;class E basic helix-loop-helix protein 75;glucocorticoid receptor-interacting protein-1;GRIP1;KAT13C;NCoA-2;nuclear receptor coactivator 2;p160 steroid receptor coactivator 2;SRC2;TIF2;transcriptional intermediary factor 2
- Weitere Details:
- The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
- Versandbedingungen:
- Blue Ice