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GTX35155
UACA antibody [AE-5]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX35155
- Zusätzliche Namen:
- NUCLING , UACA , uveal autoantigen with coiledcoil domains and ankyrin repeats , uveal autoantigen with coiled-coil domains and ankyrin repeats
- Anwendung:
- Flow Cytometry, WB, IF, ICC
- Konzentration:
- 0.2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- protein a/g purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.05% BSA, 0.05% Sodium azide.
- Immunogen:
- Nuclei of myeloid leukemia biopsy cells
- Klon:
- AE-5
- Uniprot:
- Q9BZF9
- Synonyme:
- nuclear membrane binding protein;NUCLING;uveal autoantigen with coiled-coil domains and ankyrin repeats
- Weitere Details:
- This gene encodes a protein that contains ankyrin repeats and coiled coil domains and likely plays a role in apoptosis. Studies in rodents have implicated the encoded protein in the stimulation of apoptosis and the regulation of mammary gland involution, in which the mammary gland returns to its pre-pregnant state. This protein has also been proposed to negatively regulate apoptosis based on experiments in human cell lines in which the protein was shown to interact with PRKC apoptosis WT1 regulator protein, also known as PAR-4, and inhibit translocation of the PAR-4 receptor. Autoantibodies to this protein have been identified in human patients with panuveitis and Graves' disease. Differential expression of this gene has been observed in various human cancers. [provided by RefSeq, May 2017]
- Versandbedingungen:
- Blue Ice