p27 Kip1 antibody [KIP1/769]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX34930
Zusätzliche Namen:: CDKN1B , CDKN4 , KIP1 , MEN1B , MEN4 , P27KIP1 , cyclin dependent kinase inhibitor 1B , p27 kip1
Anwendung:: Flow Cytometry, WB, IHC-P, IF, ICC
Konzentration:: 0.2 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant full-length human CDKN1B protein
Klon:: KIP1/769
Uniprot:: P46527
Synonyme:: CDKN4;cyclin-dependent kinase inhibitor 1B;cyclin-dependent kinase inhibitor 1B (p27, Kip1);Cyclin-dependent kinase inhibitor p27;KIP1;MEN1B;MEN4;P27KIP1
Weitere Details:: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]

Versandbedingungen:: Blue Ice