MCM7 antibody [SPM379]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX34821
Zusätzliche Namen:: CDC47 , MCM2 , MCM7 , P1.1MCM3 , P1CDC47 , P85MCM , PNAS146 , PPP1R104 , minichromosome maintenance complex component 7
Anwendung:: Flow Cytometry, WB, IHC-P, IF, ICC
Konzentration:: 0.2 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant human hCDC47 protein
Klon:: SPM379
Uniprot:: P33993
Synonyme:: CDC47;CDC47 homolog;DNA replication licensing factor MCM7;homolog of S. cerevisiae Cdc47;MCM2;minichromosome maintenance deficient 7;P1.1-MCM3;P1CDC47;P85MCM;PNAS146;PPP1R104;protein phosphatase 1, regulatory subunit 104
Weitere Details:: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice