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GTX34799

Insulin antibody [IRDN/805]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX34799
Zusätzliche Namen:
IDDM , IDDM1 , IDDM2 , ILPR , INS , IRDN , MODY10 , insulin , Insulin
Anwendung:
IHC-P
Konzentration:
0.2 mg/ml
Physischer Zustand:
Liquid
Aufreinigung:
protein a/g purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Bovine, Human, Mouse, Porcine, Rabbit
Buffer:
PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:
Recombinant INS protein
Klon:
IRDN/805
Uniprot:
P01308
Synonyme:
IDDM;IDDM1;IDDM2;ILPR;insulin;IRDN;MODY10;PNDM4;preproinsulin;proinsulin
Weitere Details:
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2019]
Versandbedingungen:
Blue Ice