Bax antibody [2D2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX34422
Zusätzliche Namen:: BAX , BCL2 associated X, apoptosis regulator , BCL2L4 , Bax
Anwendung:: Flow Cytometry, WB, IHC-P, IF, ICC
Konzentration:: 0.2 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
Klon:: 2D2
Uniprot:: Q07812
Synonyme:: apoptosis regulator BAX;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;bcl-2-like protein 4;BCL2 associated X protein;BCL2-associated X protein omega;bcl2-L-4;BCL2L4
Weitere Details:: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice