GTX34370
Factor VIII antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX34370
- Zusätzliche Namen:
- AHF,DXS1253E,F8,F8B,F8C,FVIII,HEMA,coagulation factor VIII,Factor VIII
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.5% BSA, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Synthesized peptide derived from human Factor VIII at 2130-2210 aa, C-terminal.
- Uniprot:
- P00451
- Synonyme:
- AHF;antihemophilic factor;coagulation factor VIII;coagulation factor VIII A1 domain;coagulation factor VIII C2 domain;coagulation factor VIII, procoagulant component;coagulation factor VIIIc;DXS1253E;F8B;F8C;factor VIII F8B;FVIII;HEMA;Procoagulant component
- Weitere Details:
- This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice