PRDM12 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX34139
Zusätzliche Namen:: HSAN8,PFM9,PR/SET domain 12,PRDM12
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.5% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Synthesized peptide derived from human PRDM12 at 160-240 aa, Internal.
Uniprot:: Q9H4Q4
Synonyme:: HSAN8;PFM9;PR domain containing 12;PR domain zinc finger protein 12;PR domain-containing protein 12
Weitere Details:: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017]