HIF1 beta antibody [4C5]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX34039
Zusätzliche Namen:: ARNT,HIF1B,HIF1BETA,HIF1beta,TANGO,aryl hydrocarbon receptor nuclear translocator,bHLHe2,HIF1 beta
Anwendung:: WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human, Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Mouse
Buffer:: PBS, 0.5% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant Protein
Klon:: 4C5
Uniprot:: P27540
Synonyme:: aryl hydrocarbon receptor nuclear translocator;bHLHe2;class E basic helix-loop-helix protein 2;dioxin receptor, nuclear translocator;HIF-1-beta;HIF-1beta;HIF1-beta;HIF1B;HIF1BETA;Hypoxia-inducible factor 1-beta;hypoxia-inducible factor 1, beta subunit;TANGO
Weitere Details:: This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

Versandbedingungen:: Blue Ice