GTX33440
PSMD8 antibody

Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX33440
- Zusätzliche Namen:
- proteasome 26S subunit, non-ATPase 8 , HEL-S-91n , HIP6 , HYPF , Nin1p , Rpn12 , S14 , p31
- Anwendung:
- WB, IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 101-350 of human PSMD8 (NP_002803.2).
- Uniprot:
- P48556
- Synonyme:
- 26S proteasome non-ATPase regulatory subunit 8;26S proteasome regulatory subunit p31;26S proteasome regulatory subunit RPN12;26S proteasome regulatory subunit S14;epididymis secretory sperm binding protein Li 91n;HEL-S-91n;HIP6;HYPF;Nin1p;p31;proteasome (prosome, macropain) 26S subunit, non-ATPase, 8;Rpn12;S14
- Weitere Details:
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice


