GTX33362
NOTCH3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX33362
- Zusätzliche Namen:
- notch receptor 3 , CADASIL , CADASIL1 , CASIL , IMF2 , LMNS
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- A synthetic peptide of human NOTCH3
- Uniprot:
- Q9UM47
- Synonyme:
- CADASIL;CADASIL1;CASIL;IMF2;LMNS;neurogenic locus notch homolog protein 3;notch 3;Notch homolog 3
- Weitere Details:
- This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice