GTX33196
FDPS antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX33196
- Zusätzliche Namen:
- farnesyl diphosphate synthase , FPPS , FPS , POROK9
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 120-419 of human FDPS (NP_001129293.1).
- Uniprot:
- P14324
- Synonyme:
- (2E,6E)-farnesyl diphosphate synthase;Dimethylallyltranstransferase;Farnesyl diphosphate synthase;farnesyl pyrophosphate synthase;farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase;FPP synthase;FPP synthetase;FPPS;FPS;Geranyltranstransferase;POROK9
- Weitere Details:
- This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
- Versandbedingungen:
- Blue Ice