GTX33034
BAIAP2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX33034
- Zusätzliche Namen:
- BAI1 associated protein 2 , BAP2 , FLAF3 , IRSP53
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 362-521 of human BAIAP2 (NP_059344.1).
- Uniprot:
- Q9UQB8
- Synonyme:
- BAI1 associated protein 2;BAP2;brain-specific angiogenesis inhibitor 1-associated protein 2;fas ligand-associated factor 3;FLAF3;insulin receptor substrate of 53 kDa;insulin receptor substrate p53/p58;insulin receptor substrate protein of 53 kDa;IRS-58;IRSP53;IRSp53/58;WAML;WASP and MIM like
- Weitere Details:
- The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
- Versandbedingungen:
- Blue Ice