GTX33023
TUG antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX33023
- Zusätzliche Namen:
- ASPSCR1 tether for SLC2A4, UBX domain containing , ASPCR1 , ASPL , ASPS , RCC17 , TUG , UBXD9 , UBXN9
- Anwendung:
- WB, IHC-P, IF, ICC, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 284-553 of human ASPSCR1 (NP_076988.1).
- Uniprot:
- Q9BZE9
- Synonyme:
- alveolar soft part sarcoma chromosomal region candidate gene 1 protein;alveolar soft part sarcoma chromosome region, candidate 1;alveolar soft part sarcoma locus;ASPCR1;ASPL;ASPS;ASPSCR1, UBX domain containing tether for SLC2A4;RCC17;renal cell carcinoma gene on chromosome 17;renal cell carcinoma, papillary, 17;renal papillary cell carcinoma protein 17;tether containing UBX domain for GLUT4;TUG;UBX domain protein 9;UBX domain-containing protein 9;UBXD9;UBXN9
- Weitere Details:
- The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]
- Versandbedingungen:
- Blue Ice