GTX32896
SSB antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32896
- Zusätzliche Namen:
- small RNA binding exonuclease protection factor La , LARP3 , La , La/SSB
- Anwendung:
- WB, IHC-P, IF, ICC, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB (NP_003133.1).
- Uniprot:
- P05455
- Synonyme:
- autoantigen La;La;la autoantigen;La ribonucleoprotein;La ribonucleoprotein domain family, member 3;La/SSB;LARP3;lupus La antigen;lupus La protein;sjoegren syndrome type B antigen;Sjogren syndrome antigen B;SS-B;SS-B/La protein
- Weitere Details:
- The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014]
- Versandbedingungen:
- Blue Ice