GTX32869
SF3B2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32869
- Zusätzliche Namen:
- splicing factor 3b subunit 2 , Cus1 , SAP145 , SF3B145 , SF3b1 , SF3b150
- Anwendung:
- WB, IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 616-895 of human SF3B2 (NP_006833.2).
- Uniprot:
- Q13435
- Synonyme:
- Cus1;pre-mRNA splicing factor SF3b 145 kDa subunit;Pre-mRNA-splicing factor SF3b 145 kDa subunit;SAP 145;SAP145;SF3b1;SF3B145;SF3b150;spliceosome associated protein 145;Spliceosome-associated protein 145;splicing factor 3B subunit 2;splicing factor 3b, subunit 2, 145kD;splicing factor 3b, subunit 2, 145kDa
- Weitere Details:
- This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice