GTX32832
Rad50 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32832
- Zusätzliche Namen:
- RAD50 double strand break repair protein , NBSLD , RAD502 , hRad50
- Anwendung:
- WB, IHC-P, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RAD50 (NP_005723.2).
- Uniprot:
- Q92878
- Synonyme:
- DNA repair protein RAD50;hRad50;NBSLD;RAD50 homolog, double strand break repair protein;RAD502
- Weitere Details:
- The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
- Versandbedingungen:
- Blue Ice