GTX32714
MBTPS1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32714
- Zusätzliche Namen:
- membrane bound transcription factor peptidase, site 1 , PCSK8 , S1P , SKI-1
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 803-1052 of human MBTPS1 (NP_003782.1).
- Uniprot:
- Q14703
- Synonyme:
- endopeptidase S1P;membrane-bound transcription factor site-1 protease;PCSK8;proprotein convertase subtilisin/kexin type 8;S1P;SEDKF;site-1 protease;SKI-1;subtilisin/kexin isozyme-1;Subtilisin/kexin-isozyme 1
- Weitere Details:
- This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]
- Versandbedingungen:
- Blue Ice