GTX32707
LH1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32707
- Zusätzliche Namen:
- procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 , EDS6 , EDSKCL1 , LH , LH1 , LLH , PLOD
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.05% ProClin 300.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 488-727 of human PLOD1 (NP_000293.2).
- Uniprot:
- Q02809
- Synonyme:
- EDS6;EDSKCL1;LH;LH1;LLH;lysine hydroxylase;lysyl hydroxlase 1;Lysyl hydroxylase 1;PLOD;procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1;procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
- Weitere Details:
- Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
- Versandbedingungen:
- Blue Ice