GTX32234
PFKFB2 (phospho Ser483) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32234
- Zusätzliche Namen:
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 , PFK-2/FBPase-2
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of PFKFB2. The exact sequence is proprietary.
- Uniprot:
- O60825
- Synonyme:
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6PF-2-K/Fru-2,6-P2ase 2;6PF-2-K/Fru-2,6-P2ASE heart-type isozyme;fructose-2,6-bisphosphatase, cardiac isozyme;PFK-2/FBPase-2;PFK/FBPase 2;PFKFB, cardiac
- Weitere Details:
- The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice