GTX32158
PACS1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32158
- Zusätzliche Namen:
- phosphofurin acidic cluster sorting protein 1 , MRD17 , SHMS
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1.The immunogen is located within amino acids 430 - 480 of PACS1.
- Uniprot:
- Q6VY07
- Synonyme:
- cytosolic sorting protein PACS-1;MRD17;PACS-1;phosphofurin acidic cluster sorting protein 1;SHMS
- Weitere Details:
- This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice