GTX32148
GLIS2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32148
- Zusätzliche Namen:
- GLIS family zinc finger 2 , NKL , NPHP7
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2.The immunogen is located within amino acids 260 - 310 of GLIS2.
- Uniprot:
- Q9BZE0
- Synonyme:
- GLI-similar 2;Kruppel-like zinc finger protein GLIS2;nephrocystin-7;neuronal Krueppel-like protein;NKL;NPHP7;zinc finger protein GLIS2
- Weitere Details:
- This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010]
- Versandbedingungen:
- Blue Ice