GTX32148-PEP
GLIS2 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX32148-PEP
- Zusätzliche Namen:
- Glis Family Zinc Finger 2 , Nkl , Nphp7 , Glis2
- Anwendung:
- Neutralisation
- Konzentration:
- 200 ug/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- GLIS family zinc finger 2
- Spezies:
- Human
- Synonyme:
- GLI-similar 2;Kruppel-like zinc finger protein GLIS2;nephrocystin-7;neuronal Krueppel-like protein;NKL;NPHP7;zinc finger protein GLIS2
- Weitere Details:
- This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010]
- Versandbedingungen:
- Dry Ice