GTX31990
NLRP13 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31990
- Zusätzliche Namen:
- NLR family pyrin domain containing 13 , CLR19.7 , NALP13 , NOD14 , PAN13
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- NALP13 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NALP13.The immunogen is located within amino acids 150 - 200 of NALP13.
- Uniprot:
- Q86W25
- Synonyme:
- CLR19.7;NACHT, leucine rich repeat and PYD containing 13;NACHT, LRR and PYD containing protein 13;NACHT, LRR and PYD domains-containing protein 13;NALP13;NOD14;nucleotide-binding oligomerization domain protein 14;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13;PAN13
- Weitere Details:
- NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
- Versandbedingungen:
- Blue Ice