GTX31864
KEAP1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX31864
- Zusätzliche Namen:
- kelch like ECH associated protein 1 , INrf2 , KLHL19
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- KEAP1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human KEAP1.The immunogen is located within the last 50 amino acids of KEAP1.
- Uniprot:
- Q14145
- Synonyme:
- cytosolic inhibitor of Nrf2;INrf2;KEAP1 delta C;kelch-like ECH-associated protein 1;kelch-like family member 19;kelch-like protein 19;KLHL19
- Weitere Details:
- This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice